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A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells

Secretory cells in glands and the nervous system frequently package and store proteins destined for regulated secretion in dense-core granules (DCGs), which disperse when released from the cell surface. Despite the relevance of this dynamic process to diseases such as diabetes and human neurodegener...

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Detalles Bibliográficos
Autores principales: Wells, Adam, Mendes, Cláudia C., Castellanos, Felix, Mountain, Phoebe, Wright, Tia, Wainwright, S. Mark, Stefana, M. Irina, Harris, Adrian L., Goberdhan, Deborah C. I., Wilson, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602379/
https://www.ncbi.nlm.nih.gov/pubmed/37844085
http://dx.doi.org/10.1371/journal.pgen.1010979