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The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system

The ability to form a dormant spore is essential for the survival of the anaerobic pathogen, Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of sporulation is governed by the master regulator of sporulation, Spo0A, which is activated by phosphorylation. Mult...

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Detalles Bibliográficos
Autores principales: Edwards, Adrianne N., McBride, Shonna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602386/
https://www.ncbi.nlm.nih.gov/pubmed/37844084
http://dx.doi.org/10.1371/journal.pgen.1010841