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The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system
The ability to form a dormant spore is essential for the survival of the anaerobic pathogen, Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of sporulation is governed by the master regulator of sporulation, Spo0A, which is activated by phosphorylation. Mult...
Autores principales: | Edwards, Adrianne N., McBride, Shonna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602386/ https://www.ncbi.nlm.nih.gov/pubmed/37844084 http://dx.doi.org/10.1371/journal.pgen.1010841 |
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