VHL-deficiency leads to reductive stress in renal cells

Heritable renal cancer syndromes (RCS) are associated with numerous chromosomal alterations including inactivating mutations in von Hippel-Lindau (VHL) gene. Here we identify a novel aspect of the phenotype in VHL-deficient human renal cells. We call it reductive stress as it is characterised by inc...

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Detalles Bibliográficos
Autores principales: Vellama, Hans, Eskla, Kattri-Liis, Eichelmann, Hillar, Hüva, Andria, Tennant, Daniel A., Thakker, Alpesh, Roberts, Jennie, Jagomäe, Toomas, Porosk, Rando, Laisk, Agu, Oja, Vello, Rämma, Heikko, Volke, Vallo, Vasar, Eero, Luuk, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602395/
https://www.ncbi.nlm.nih.gov/pubmed/37506952
http://dx.doi.org/10.1016/j.freeradbiomed.2023.07.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602395/
https://www.ncbi.nlm.nih.gov/pubmed/37506952
http://dx.doi.org/10.1016/j.freeradbiomed.2023.07.029

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