LRRK2 Gly2019Ser Mutation Promotes ER Stress via Interacting with THBS1/TGF‐β1 in Parkinson's Disease

The gene mutations of LRRK2, which encodes leucine‐rich repeat kinase 2 (LRRK2), are associated with one of the most prevalent monogenic forms of Parkinson's disease (PD). However, the potential effectors of the Gly2019Ser (G2019S) mutation remain unknown. In this study, the authors investigate...

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Detalles Bibliográficos
Autores principales: Yao, Longping, Lu, Fengfei, Koc, Sumeyye, Zheng, Zijian, Wang, Baoyan, Zhang, Shizhong, Skutella, Thomas, Lu, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602550/
https://www.ncbi.nlm.nih.gov/pubmed/37672887
http://dx.doi.org/10.1002/advs.202303711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602550/
https://www.ncbi.nlm.nih.gov/pubmed/37672887
http://dx.doi.org/10.1002/advs.202303711

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