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LRRK2 Gly2019Ser Mutation Promotes ER Stress via Interacting with THBS1/TGF‐β1 in Parkinson's Disease
The gene mutations of LRRK2, which encodes leucine‐rich repeat kinase 2 (LRRK2), are associated with one of the most prevalent monogenic forms of Parkinson's disease (PD). However, the potential effectors of the Gly2019Ser (G2019S) mutation remain unknown. In this study, the authors investigate...
Autores principales: | Yao, Longping, Lu, Fengfei, Koc, Sumeyye, Zheng, Zijian, Wang, Baoyan, Zhang, Shizhong, Skutella, Thomas, Lu, Guohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602550/ https://www.ncbi.nlm.nih.gov/pubmed/37672887 http://dx.doi.org/10.1002/advs.202303711 |
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