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Use of Deep‐Learning Assisted Assessment of Cardiac Parameters in Zebrafish to Discover Cyanidin Chloride as a Novel Keap1 Inhibitor Against Doxorubicin‐Induced Cardiotoxicity

Doxorubicin‐induced cardiomyopathy (DIC) brings tough clinical challenges as well as continued demand in developing agents for adjuvant cardioprotective therapies. Here, a zebrafish phenotypic screening with deep‐learning assisted multiplex cardiac functional analysis using motion videos of larval h...

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Detalles Bibliográficos
Autores principales: Liu, Changtong, Wang, Yingchao, Zeng, Yixin, Kang, Zirong, Zhao, Hong, Qi, Kun, Wu, Hongzhi, Zhao, Lu, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602559/
https://www.ncbi.nlm.nih.gov/pubmed/37679058
http://dx.doi.org/10.1002/advs.202301136