Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

Mostrar otras versiones (1)

Catalytic signaling outputs of protein kinases are dynamically regulated by an array of structural mechanisms, including allosteric interactions mediated by intrinsically disordered segments flanking the conserved catalytic domain. The doublecortin-like kinases (DCLKs) are a family of microtubule-as...

Descripción completa

Detalles Bibliográficos
Autores principales: Venkat, Aarya, Watterson, Grace, Byrne, Dominic P, O'Boyle, Brady, Shrestha, Safal, Gravel, Nathan, Fairweather, Emma E, Daly, Leonard A, Bunn, Claire, Yeung, Wayland, Aggarwal, Ishan, Katiyar, Samiksha, Eyers, Claire E, Eyers, Patrick A, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602587/
https://www.ncbi.nlm.nih.gov/pubmed/37883155
http://dx.doi.org/10.7554/eLife.87958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602587/
https://www.ncbi.nlm.nih.gov/pubmed/37883155
http://dx.doi.org/10.7554/eLife.87958

Ejemplares similares