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Idiosyncratic and dose-dependent epistasis drives variation in tomato fruit size

Epistasis between genes is traditionally studied using mutations that eliminate protein activity, but most natural genetic variation is in cis-regulatory DNA and influences gene expression and function quantitatively. Here, we use natural and engineered cis-regulatory alleles in a plant stem cell ci...

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Detalles Bibliográficos
Autores principales: Aguirre, Lyndsey, Hendelman, Anat, Hutton, Samuel F., McCandlish, David M., Lippman, Zachary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602613/
https://www.ncbi.nlm.nih.gov/pubmed/37856609
http://dx.doi.org/10.1126/science.adi5222