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Idiosyncratic and dose-dependent epistasis drives variation in tomato fruit size
Epistasis between genes is traditionally studied using mutations that eliminate protein activity, but most natural genetic variation is in cis-regulatory DNA and influences gene expression and function quantitatively. Here, we use natural and engineered cis-regulatory alleles in a plant stem cell ci...
Autores principales: | Aguirre, Lyndsey, Hendelman, Anat, Hutton, Samuel F., McCandlish, David M., Lippman, Zachary B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602613/ https://www.ncbi.nlm.nih.gov/pubmed/37856609 http://dx.doi.org/10.1126/science.adi5222 |
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