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Reclassification of variants of tumor suppressor genes based on Sanger RNA sequencing without NMD inhibition

Introduction: RNA sequence analysis can be effectively used to identify aberrant splicing, and tumor suppressor genes are adequate targets considering their loss-of-function mechanisms. Sanger sequencing is the simplest method for RNA sequence analysis; however, because of its insufficient sensitivi...

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Detalles Bibliográficos
Autores principales: Ha, Changhee, Jang, Ja-Hyun, Kim, Young-gon, Kim, Jong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602670/
https://www.ncbi.nlm.nih.gov/pubmed/37900184
http://dx.doi.org/10.3389/fgene.2023.1283611