Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome

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There is an urgent need to improve the translational validity of Alzheimer's disease (AD) mouse models. Introducing genetic background diversity in AD mouse models has been proposed as a way to increase validity and enable the discovery of previously uncharacterized genetic contributions to AD...

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Detalles Bibliográficos
Autores principales: Hurst, Cheyenne D., Dunn, Amy R., Dammer, Eric B., Duong, Duc M., Shapley, Sarah M., Seyfried, Nicholas T., Kaczorowski, Catherine C., Johnson, Erik C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602695/
https://www.ncbi.nlm.nih.gov/pubmed/37901791
http://dx.doi.org/10.3389/fnagi.2023.1239116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602695/
https://www.ncbi.nlm.nih.gov/pubmed/37901791
http://dx.doi.org/10.3389/fnagi.2023.1239116

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