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Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils

INTRODUCTION: Elevated neutrophil counts in blood, sputum, or lung have been associated with poor clinical outcomes and more severe disease in patients with type 2 asthma. In the phase 3 LIBERTY ASTHMA QUEST (NCT02414854), add-on dupilumab 200 and 300 mg every 2 weeks compared with matched placebo s...

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Detalles Bibliográficos
Autores principales: Bleecker, Eugene R., Panettieri, Reynold A., Lugogo, Njira L., Corren, Jonathan, Daizadeh, Nadia, Jacob-Nara, Juby A., Deniz, Yamo, Rowe, Paul J., Khodzhayev, Angela, Soler, Xavier, Ferro, Thomas J., Hansen, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602700/
https://www.ncbi.nlm.nih.gov/pubmed/37901346
http://dx.doi.org/10.1155/2023/9943584