Super enhancer-driven core transcriptional regulatory circuitry crosstalk with cancer plasticity and patient mortality in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer. Core transcriptional regulatory circuitry (CRC) consists of autoregulated transcription factors (TFs) and their enhancers, which dominate gene expression programs and control cell fate. However, there is limite...

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Detalles Bibliográficos
Autores principales: Shi, Wensheng, Zhong, Bowen, Dong, Jiaming, Hu, Xiheng, Li, Lingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602724/
https://www.ncbi.nlm.nih.gov/pubmed/37900187
http://dx.doi.org/10.3389/fgene.2023.1258862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602724/
https://www.ncbi.nlm.nih.gov/pubmed/37900187
http://dx.doi.org/10.3389/fgene.2023.1258862

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