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Super enhancer-driven core transcriptional regulatory circuitry crosstalk with cancer plasticity and patient mortality in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer. Core transcriptional regulatory circuitry (CRC) consists of autoregulated transcription factors (TFs) and their enhancers, which dominate gene expression programs and control cell fate. However, there is limite...
Autores principales: | Shi, Wensheng, Zhong, Bowen, Dong, Jiaming, Hu, Xiheng, Li, Lingfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602724/ https://www.ncbi.nlm.nih.gov/pubmed/37900187 http://dx.doi.org/10.3389/fgene.2023.1258862 |
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