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Mapping the recognition pathway of cyclobutane pyrimidine dimer in DNA by Rad4/XPC

UV radiation-induced DNA damages have adverse effects on genome integrity and cellular function. The most prevalent UV-induced DNA lesion is the cyclobutane pyrimidine dimer (CPD), which can cause skin disorders and cancers in humans. Rad4/XPC is a damage sensing protein that recognizes and repairs...

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Detalles Bibliográficos
Autores principales: Jakhar, Nikhil, Prabhakant, Akshay, Krishnan, Marimuthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602858/
https://www.ncbi.nlm.nih.gov/pubmed/37757853
http://dx.doi.org/10.1093/nar/gkad730