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Mapping the recognition pathway of cyclobutane pyrimidine dimer in DNA by Rad4/XPC
UV radiation-induced DNA damages have adverse effects on genome integrity and cellular function. The most prevalent UV-induced DNA lesion is the cyclobutane pyrimidine dimer (CPD), which can cause skin disorders and cancers in humans. Rad4/XPC is a damage sensing protein that recognizes and repairs...
Autores principales: | Jakhar, Nikhil, Prabhakant, Akshay, Krishnan, Marimuthu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602858/ https://www.ncbi.nlm.nih.gov/pubmed/37757853 http://dx.doi.org/10.1093/nar/gkad730 |
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