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High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase

The first step in gene expression is the transcription of DNA sequences into RNA. Regulation at the level of transcription leads to changes in steady-state concentrations of RNA transcripts, affecting the flux of downstream functions and ultimately cellular phenotypes. Changes in transcript levels a...

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Detalles Bibliográficos
Autores principales: Jensen, Drake, Ruiz Manzano, Ana, Rector, Maxwell, Tomko, Eric J, Record, M Thomas, Galburt, Eric A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602862/
https://www.ncbi.nlm.nih.gov/pubmed/37739412
http://dx.doi.org/10.1093/nar/gkad761