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Cleavage kinetics of human mitochondrial RNase P and contribution of its non-nuclease subunits

RNase P is the endonuclease responsible for the 5′ processing of precursor tRNAs (pre-tRNAs). Unlike the single-subunit protein-only RNase P (PRORP) found in plants or protists, human mitochondrial RNase P is a multi-enzyme assembly that in addition to the homologous PRORP subunit comprises a methyl...

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Detalles Bibliográficos
Autores principales: Vilardo, Elisa, Toth, Ursula, Hazisllari, Enxhi, Hartmann, Roland K, Rossmanith, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602865/
https://www.ncbi.nlm.nih.gov/pubmed/37779095
http://dx.doi.org/10.1093/nar/gkad713