Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination

Homologous recombination (HR) requires bidirectional end resection initiated by a nick formed close to a DNA double-strand break (DSB), dysregulation favoring error-prone DNA end-joining pathways. Here we investigate the role of the ATAD5, a PCNA unloading protein, in short-range end resection, long...

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Detalles Bibliográficos
Autores principales: Park, Su Hyung, Kim, Namwoo, Kang, Nalae, Ryu, Eunjin, Lee, Eun A, Ra, Jae Sun, Gartner, Anton, Kang, Sukhyun, Myung, Kyungjae, Lee, Kyoo-young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602867/
https://www.ncbi.nlm.nih.gov/pubmed/37739427
http://dx.doi.org/10.1093/nar/gkad776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602867/
https://www.ncbi.nlm.nih.gov/pubmed/37739427
http://dx.doi.org/10.1093/nar/gkad776

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