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Diverse regulatory pathways modulate bet hedging of competence induction in epigenetically-differentiated phase variants of Streptococcus pneumoniae

Despite enabling Streptococcus pneumoniae to acquire antibiotic resistance and evade vaccine-induced immunity, transformation occurs at variable rates across pneumococci. Phase variants of isolate RMV7, distinguished by altered methylation patterns driven by the translocating variable restriction-mo...

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Detalles Bibliográficos
Autores principales: Kwun, Min Jung, Ion, Alexandru V, Oggioni, Marco R, Bentley, Stephen D, Croucher, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602874/
https://www.ncbi.nlm.nih.gov/pubmed/37757859
http://dx.doi.org/10.1093/nar/gkad760