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Distinct RPA functions promote eukaryotic DNA replication initiation and elongation

Replication protein A (RPA) binds single-stranded DNA (ssDNA) and serves critical functions in eukaryotic DNA replication, the DNA damage response, and DNA repair. During DNA replication, RPA is required for extended origin DNA unwinding and DNA synthesis. To determine the requirements for RPA durin...

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Detalles Bibliográficos
Autores principales: Pike, Alexandra M, Friend, Caitlin M, Bell, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602884/
https://www.ncbi.nlm.nih.gov/pubmed/37739410
http://dx.doi.org/10.1093/nar/gkad765