Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase

Telomeric C-rich repeated DNA sequences fold into tetrahelical i-motif structures in vitro at acidic pH. While studies have suggested that i-motifs may form in cells, little is known about their potential role in human telomere biology. In this study, we explore the effect of telomeric C-strands and...

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Detalles Bibliográficos
Autores principales: El-Khoury, Roberto, Roman, Morgane, Assi, Hala Abou, Moye, Aaron L, Bryan, Tracy M, Damha, Masad J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602923/
https://www.ncbi.nlm.nih.gov/pubmed/37742080
http://dx.doi.org/10.1093/nar/gkad764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602923/
https://www.ncbi.nlm.nih.gov/pubmed/37742080
http://dx.doi.org/10.1093/nar/gkad764

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