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Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase
Telomeric C-rich repeated DNA sequences fold into tetrahelical i-motif structures in vitro at acidic pH. While studies have suggested that i-motifs may form in cells, little is known about their potential role in human telomere biology. In this study, we explore the effect of telomeric C-strands and...
Autores principales: | El-Khoury, Roberto, Roman, Morgane, Assi, Hala Abou, Moye, Aaron L, Bryan, Tracy M, Damha, Masad J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602923/ https://www.ncbi.nlm.nih.gov/pubmed/37742080 http://dx.doi.org/10.1093/nar/gkad764 |
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