Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery

Translational readthrough of UGA stop codons by selenocysteine-specific tRNA (tRNA(Sec)) enables the synthesis of selenoproteins. Seryl-tRNA synthetase (SerRS) charges tRNA(Sec) with serine, which is modified into selenocysteine and delivered to the ribosome by a designated elongation factor (eEFSec...

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Detalles Bibliográficos
Autores principales: Liu, Ze, Wang, Justin, Shi, Yi, Yee, Brian A, Terrey, Markus, Zhang, Qian, Lee, Jenq-Chang, Lin, Kuo-I, Wang, Andrew H-J, Ackerman, Susan L, Yeo, Gene W, Cui, Haissi, Yang, Xiang-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602924/
https://www.ncbi.nlm.nih.gov/pubmed/37739431
http://dx.doi.org/10.1093/nar/gkad773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602924/
https://www.ncbi.nlm.nih.gov/pubmed/37739431
http://dx.doi.org/10.1093/nar/gkad773

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