Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation

Transcription enhancers are essential activators of V(D)J recombination that orchestrate non-coding transcription through complementary, unrearranged gene segments. How transcription is coordinately increased at spatially distinct promoters, however, remains poorly understood. Using the murine immun...

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Detalles Bibliográficos
Autores principales: Gao, Zeqian, Smith, Alastair L, Scott, James N F, Bevington, Sarah L, Boyes, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602925/
https://www.ncbi.nlm.nih.gov/pubmed/37702072
http://dx.doi.org/10.1093/nar/gkad741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602925/
https://www.ncbi.nlm.nih.gov/pubmed/37702072
http://dx.doi.org/10.1093/nar/gkad741

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