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In vitro antineoplastic effects of MK0752 in HPV-positive head and neck squamous cell carcinoma

PURPOSE: Gamma-secretase inhibitor MK0752 has shown a high therapeutic potential in different solid malignant tumors. Up to now, its antineoplastic effects were not investigated in head and neck squamous cell carcinoma (HNSCC) and particularly in human-papillomavirus (HPV)-positive tumors. METHODS:...

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Detalles Bibliográficos
Autores principales: Varatanovic, Sara, Stoiber, Stefan, Haas, Markus, Lein, Alexander, Kadletz-Wanke, Lorenz, Brkic, Faris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602957/
https://www.ncbi.nlm.nih.gov/pubmed/37587308
http://dx.doi.org/10.1007/s00432-023-05269-x