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Enhanced antibiotic release from bone cement spacers utilizing dual antibiotic loading with elevated vancomycin concentrations in two-stage revision for periprosthetic joint infection

PURPOSE: Antibiotic loaded bone cement spacers provide high local antibiotic concentrations, preserve bone stock, and reduce soft tissue contractions. The objective of this in-vitro study was to compare antibiotic release from spacers, aiming to discover the most optimal preparation and identify mod...

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Detalles Bibliográficos
Autores principales: Lunz, Andre, Schonhoff, Mareike, Omlor, Georg W., Knappe, Kevin, Bangert, Yannic, Lehner, Burkhard, Renkawitz, Tobias, Jaeger, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602962/
https://www.ncbi.nlm.nih.gov/pubmed/37566227
http://dx.doi.org/10.1007/s00264-023-05922-7