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Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations

Extracellular vesicle (EV)‐carried miRNAs can influence gene expression and functional phenotypes in recipient cells. Argonaute 2 (Ago2) is a key miRNA‐binding protein that has been identified in EVs and could influence RNA silencing. However, Ago2 is in a non‐vesicular form in serum and can be an E...

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Detalles Bibliográficos
Autores principales: Jimenez, Lizandra, Barman, Bahnisikha, Jung, Youn Jae, Cocozza, Lauren, Krystofiak, Evan, Saffold, Cherie, Vickers, Kasey C., Wilson, John T., Dawson, T. Renee, Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603024/
https://www.ncbi.nlm.nih.gov/pubmed/37885043
http://dx.doi.org/10.1002/jev2.12366