Cargando…
CNS tumor stroma transcriptomics identify perivascular fibroblasts as predictors of immunotherapy resistance in glioblastoma patients
Excessive deposition of extracellular matrix (ECM) is a hallmark of solid tumors; however, it remains poorly understood which cellular and molecular components contribute to the formation of ECM stroma in central nervous system (CNS) tumors. Here, we undertake a pan-CNS analysis of retrospective gen...
Autores principales: | Zarodniuk, Maksym, Steele, Alexander, Lu, Xin, Li, Jun, Datta, Meenal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603041/ https://www.ncbi.nlm.nih.gov/pubmed/37884531 http://dx.doi.org/10.1038/s41525-023-00381-w |
Ejemplares similares
-
Pan-cancer transcriptomic analysis of CNS tumor stroma identifies a population of perivascular fibroblasts that predict poor immunotherapy response in glioblastoma patients
por: Zarodniuk, Maksym, et al.
Publicado: (2023) -
SDPS-30 ANALYSIS OF THE BRAIN TUMOR MATRISOME REVEALS CANCER ASSOCIATED FIBROBLASTS PREDICT POOR IMMUNOTHERAPY RESPONSE IN GLIOBLASTOMA PATIENTS
por: Zarodniuk, Maksym, et al.
Publicado: (2023) -
Single-cell mechanical analysis reveals viscoelastic similarities between normal and neoplastic brain cells
por: Onwudiwe, Killian, et al.
Publicado: (2023) -
The Configuration of the Perivascular System Transporting Macromolecules in the CNS
por: Durcanova, Beata, et al.
Publicado: (2019) -
The CNS and the Brain Tumor Microenvironment: Implications for Glioblastoma Immunotherapy
por: Desland, Fiona A., et al.
Publicado: (2020)