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Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling

Despite the diverse roles of tripartite motif (Trim)-containing proteins in the regulation of autophagy, the innate immune response, and cell differentiation, their roles in skeletal diseases are largely unknown. We recently demonstrated that Trim21 plays a crucial role in regulating osteoblast (OB)...

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Detalles Bibliográficos
Autores principales: Liu, Ri-Xu, Gu, Rong-He, Li, Zhi-Peng, Hao, Zhi-Quan, Hu, Qin-Xiao, Li, Zhen-Yan, Wang, Xiao-Gang, Tang, Wang, Wang, Xiao-He, Zeng, Yu-Kai, Li, Zhen-Wei, Dong, Qiu, Zhu, Xiao-Feng, Chen, Di, Zhao, Ke-Wei, Zhang, Rong-Hua, Zha, Zhen-Gang, Zhang, Huan-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603047/
https://www.ncbi.nlm.nih.gov/pubmed/37884520
http://dx.doi.org/10.1038/s41413-023-00296-3