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Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex
Inhibiting protein–protein interactions of the Myc family is a viable pharmacological strategy for modulation of the levels of Myc oncoproteins in cancer. Aurora A kinase (AurA) and N-Myc interaction is one of the most attractive targets of this strategy because formation of this complex blocks prot...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603048/ https://www.ncbi.nlm.nih.gov/pubmed/37884585 http://dx.doi.org/10.1038/s41598-023-45272-3 |