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Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen

Adjuvants can enhance vaccine immunogenicity, but their mechanism of action is often incompletely understood, hampering rapid applicability for pandemic vaccines. Herein, we characterized the cellular and molecular activity of adjuvant formulations available for pre-clinical evaluation, including se...

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Detalles Bibliográficos
Autores principales: Doss-Gollin, Simon, Thomas, Sanya, Brook, Byron, Abedi, Kimia, Lebas, Célia, Auderset, Floriane, Lugo-Rodriguez, Yamile, Sanchez-Schmitz, Guzman, Dowling, David J., Levy, Ofer, van Haren, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603059/
https://www.ncbi.nlm.nih.gov/pubmed/37884538
http://dx.doi.org/10.1038/s41541-023-00759-y