Insights into next generation sequencing guided antibody selection strategies

Therapeutic antibody discovery often relies on in-vitro display methods to identify lead candidates. Assessing selected output diversity traditionally involves random colony picking and Sanger sequencing, which has limitations. Next-generation sequencing (NGS) offers a cost-effective solution with i...

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Detalles Bibliográficos
Autores principales: Erasmus, M. Frank, Ferrara, Fortunato, D’Angelo, Sara, Spector, Laura, Leal-Lopes, Camila, Teixeira, André A., Sørensen, Jesper, Nagpal, Suhani, Perea-Schmittle, Kathryn, Choudhary, Alok, Honnen, William, Calianese, David, Antonio Rodriguez Carnero, Luis, Cocklin, Simon, Greiff, Victor, Pinter, Abraham, Bradbury, Andrew R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603065/
https://www.ncbi.nlm.nih.gov/pubmed/37884618
http://dx.doi.org/10.1038/s41598-023-45538-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603065/
https://www.ncbi.nlm.nih.gov/pubmed/37884618
http://dx.doi.org/10.1038/s41598-023-45538-w

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