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Development of an accelerated cellular model for early changes in Alzheimer’s disease

Alzheimer’s Disease (AD) is a leading cause of dementia characterized by amyloid plaques and neurofibrillary tangles, and its pathogenesis remains unclear. Current cellular models for AD often require several months to exhibit phenotypic features due to the lack of an aging environment in vitro. Lam...

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Detalles Bibliográficos
Autores principales: Xue, Huijing, Gate, Sylvester, Gentry, Emma, Losert, Wolfgang, Cao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603068/
https://www.ncbi.nlm.nih.gov/pubmed/37884611
http://dx.doi.org/10.1038/s41598-023-45826-5