ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production

Insulin resistance is associated with many pathological conditions, and an in-depth understanding of the mechanisms involved is necessary to improve insulin sensitivity. Here, we show that ZFYVE28 expression is decreased in insulin-sensitive obese individuals but increased in insulin-resistant indiv...

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Detalles Bibliográficos
Autores principales: Yu, Liang, Xu, Mengchen, Yan, Yupeng, Huang, Shuchen, Yuan, Mengmeng, Cui, Bing, Lv, Cheng, Zhang, Yu, Wang, Hongrui, Jin, Xiaolei, Hui, Rutai, Wang, Yibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603069/
https://www.ncbi.nlm.nih.gov/pubmed/37884540
http://dx.doi.org/10.1038/s41467-023-42657-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603069/
https://www.ncbi.nlm.nih.gov/pubmed/37884540
http://dx.doi.org/10.1038/s41467-023-42657-w

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