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ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production
Insulin resistance is associated with many pathological conditions, and an in-depth understanding of the mechanisms involved is necessary to improve insulin sensitivity. Here, we show that ZFYVE28 expression is decreased in insulin-sensitive obese individuals but increased in insulin-resistant indiv...
Autores principales: | Yu, Liang, Xu, Mengchen, Yan, Yupeng, Huang, Shuchen, Yuan, Mengmeng, Cui, Bing, Lv, Cheng, Zhang, Yu, Wang, Hongrui, Jin, Xiaolei, Hui, Rutai, Wang, Yibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603069/ https://www.ncbi.nlm.nih.gov/pubmed/37884540 http://dx.doi.org/10.1038/s41467-023-42657-w |
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