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Practical N-to-C peptide synthesis with minimal protecting groups

Accessible drug modalities have continued to increase in number in recent years. Peptides play a central role as pharmaceuticals and biomaterials in these new drug modalities. Although traditional peptide synthesis using chain-elongation from C- to N-terminus is reliable, it produces large quantitie...

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Detalles Bibliográficos
Autores principales: Tatsumi, Toshifumi, Sasamoto, Koki, Matsumoto, Takuya, Hirano, Ryo, Oikawa, Kazuki, Nakano, Masato, Yoshida, Masaru, Oisaki, Kounosuke, Kanai, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603086/
https://www.ncbi.nlm.nih.gov/pubmed/37884638
http://dx.doi.org/10.1038/s42004-023-01030-0