Dual-target drugs against Leishmania donovani for potential novel therapeutics

Antioxidant defense mechanisms are important for a parasite to overcome oxidative stress and survive within host macrophage cells. Mitochondrial iron superoxide dismutase A (FeSODA) and trypanothione reductase (TR) are critical enzymes in the antioxidant defense mechanism of Leishmania donovani. FeS...

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Detalles Bibliográficos
Autores principales: Bora, Kushal, Sarma, Manash, Kanaujia, Shankar Prasad, Dubey, Vikash Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603092/
https://www.ncbi.nlm.nih.gov/pubmed/37884555
http://dx.doi.org/10.1038/s41598-023-45448-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603092/
https://www.ncbi.nlm.nih.gov/pubmed/37884555
http://dx.doi.org/10.1038/s41598-023-45448-x

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