RNA-based translation activators for targeted gene upregulation

Technologies capable of programmable translation activation offer strategies to develop therapeutics for diseases caused by insufficient gene expression. Here, we present “translation-activating RNAs” (taRNAs), a bifunctional RNA-based molecular technology that binds to a specific mRNA of interest a...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Liu, Huachun, Lu, Shannon S., Jones, Krysten A., Govind, Anitha P., Jeyifous, Okunola, Simmons, Christine Q., Tabatabaei, Negar, Green, William N., Holder, Jimmy. L., Tahmasebi, Soroush, George, Alfred L., Dickinson, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603104/
https://www.ncbi.nlm.nih.gov/pubmed/37884512
http://dx.doi.org/10.1038/s41467-023-42252-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603104/
https://www.ncbi.nlm.nih.gov/pubmed/37884512
http://dx.doi.org/10.1038/s41467-023-42252-z

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