A single amino acid substitution in the capsid protein of Zika virus contributes to a neurovirulent phenotype

Increasing evidence shows the African lineage Zika virus (ZIKV) displays a more severe neurovirulence compared to the Asian ZIKV. However, viral determinants and the underlying mechanisms of enhanced virulence phenotype remain largely unknown. Herein, we identify a panel of amino acid substitutions...

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Detalles Bibliográficos
Autores principales: Song, Guang-Yuan, Huang, Xing-Yao, He, Meng-Jiao, Zhou, Hang-Yu, Li, Rui-Ting, Tian, Ying, Wang, Yan, Cheng, Meng-Li, Chen, Xiang, Zhang, Rong-Rong, Zhou, Chao, Zhou, Jia, Fang, Xian-Yang, Li, Xiao-Feng, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603150/
https://www.ncbi.nlm.nih.gov/pubmed/37884553
http://dx.doi.org/10.1038/s41467-023-42676-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603150/
https://www.ncbi.nlm.nih.gov/pubmed/37884553
http://dx.doi.org/10.1038/s41467-023-42676-7

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