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A single amino acid substitution in the capsid protein of Zika virus contributes to a neurovirulent phenotype
Increasing evidence shows the African lineage Zika virus (ZIKV) displays a more severe neurovirulence compared to the Asian ZIKV. However, viral determinants and the underlying mechanisms of enhanced virulence phenotype remain largely unknown. Herein, we identify a panel of amino acid substitutions...
Autores principales: | Song, Guang-Yuan, Huang, Xing-Yao, He, Meng-Jiao, Zhou, Hang-Yu, Li, Rui-Ting, Tian, Ying, Wang, Yan, Cheng, Meng-Li, Chen, Xiang, Zhang, Rong-Rong, Zhou, Chao, Zhou, Jia, Fang, Xian-Yang, Li, Xiao-Feng, Qin, Cheng-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603150/ https://www.ncbi.nlm.nih.gov/pubmed/37884553 http://dx.doi.org/10.1038/s41467-023-42676-7 |
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