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Unidirectional alteration of methylation and hydroxymethylation at the promoters and differential gene expression in oral squamous cell carcinoma

Background: Oral squamous cell carcinoma (OSCC) is one of the most common types of cancer worldwide. Although overall losses of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) have been previously observed, a genome-wide, single-base-resolution, and simultaneous mapping of 5mC and 5hmC in...

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Detalles Bibliográficos
Autores principales: Zhao, Weizhi, Zhu, Lin, Gong, Qian, Ma, Suzhen, Xiong, Haofeng, Su, Tong, Wan, Zhengqing, Wang, Danling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603190/
https://www.ncbi.nlm.nih.gov/pubmed/37900177
http://dx.doi.org/10.3389/fgene.2023.1269084