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Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium

OBJECTIVE: The aim was to determine preoperative gut microbiota metabolites that may be associated with postoperative delirium (POD) development in patients and further study in rodents. SUMMARY BACKGROUND DATA: POD occurs in 9% to 50% of older patients undergoing anesthesia/surgery but lacks effect...

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Detalles Bibliográficos
Autores principales: Zhou, Xue, Wu, Xinbo, Wu, Yan, Yang, Liuyue, Shi, Eleanor, Ding, Weihua, Chen, Liang, Shi, Xu, Feng, Xia, Su, Chienwen, You, Zerong, Xia, Jianguo, Chen, Cynthia, Yeliseyev, Vladimir, Bry, Lynn, Xia, Suyun, Huang, Peigen, Meng, Jiawei, Houle, Timothy, Akeju, Oluwaseun, Mao, Jianren, Gerszten, Robert, Chen, Qian, Xie, Zhongcong, Shen, Shiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603211/
https://www.ncbi.nlm.nih.gov/pubmed/37185230
http://dx.doi.org/10.1097/SLA.0000000000005886