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The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

There is now evidence from multiple Phase II clinical trials that psychedelic drugs can exert long-lasting anxiolytic, anti-depressant, and anti-drug abuse (nicotine and ethanol) effects in patients. Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT...

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Detalles Bibliográficos
Autores principales: Pogorelov, Vladimir M., Rodriguiz, Ramona M., Roth, Bryan L., Wetsel, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603247/
https://www.ncbi.nlm.nih.gov/pubmed/37900918
http://dx.doi.org/10.3389/fmolb.2023.1233743