Cargando…

Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studies

The effect of combination therapies in many cancers has often been shown to be superior to that of monotherapies. This success is commonly attributed to drug synergies. Combinations of two (or more) drugs in xenograft tumor growth inhibition (TGI) studies are typically designed at fixed doses for ea...

Descripción completa

Detalles Bibliográficos
Autores principales: Melillo, Nicola, Dickinson, Jake, Tan, Lu, Mistry, Hitesh B., Huber, Heinrich J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603293/
https://www.ncbi.nlm.nih.gov/pubmed/37900154
http://dx.doi.org/10.3389/fphar.2023.1272058