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Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studies
The effect of combination therapies in many cancers has often been shown to be superior to that of monotherapies. This success is commonly attributed to drug synergies. Combinations of two (or more) drugs in xenograft tumor growth inhibition (TGI) studies are typically designed at fixed doses for ea...
Autores principales: | Melillo, Nicola, Dickinson, Jake, Tan, Lu, Mistry, Hitesh B., Huber, Heinrich J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603293/ https://www.ncbi.nlm.nih.gov/pubmed/37900154 http://dx.doi.org/10.3389/fphar.2023.1272058 |
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