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Classification of the tumor immune microenvironment and associations with outcomes in patients with metastatic melanoma treated with immunotherapies

BACKGROUND: Tumor microenvironment (TME) characteristics are potential biomarkers of response to immune checkpoint inhibitors in metastatic melanoma. This study developed a method to perform unsupervised classification of TME of metastatic melanoma. METHODS: We used multiplex immunohistochemical and...

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Detalles Bibliográficos
Autores principales: Adegoke, Nurudeen A, Gide, Tuba N, Mao, Yizhe, Quek, Camelia, Patrick, Ellis, Carlino, Matteo S, Lo, Serigne N, Menzies, Alexander Maxwell, Pires da Silva, Ines, Vergara, Ismael A, Long, Georgina, Scolyer, Richard A, Wilmott, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603328/
https://www.ncbi.nlm.nih.gov/pubmed/37865395
http://dx.doi.org/10.1136/jitc-2023-007144