Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) is a key intracellular enzyme that participates in nicotinamide adenine dinucleotide (NAD) homeostasis as well as a released cytokine (eNAMPT) that is elevated in inflammatory conditions and in cancer. In patients with breast cancer, circula...

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Detalles Bibliográficos
Autores principales: Travelli, Cristina, Colombo, Giorgia, Aliotta, Martina, Fagiani, Francesca, Fava, Natalia, De Sanctis, Rita, Grolla, Ambra A, Garcia, Joe G N, Clemente, Nausicaa, Portararo, Paola, Costanza, Massimo, Condorelli, Fabrizio, Colombo, Mario Paolo, Sangaletti, Sabina, Genazzani, Armando A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603332/
https://www.ncbi.nlm.nih.gov/pubmed/37880182
http://dx.doi.org/10.1136/jitc-2023-007010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603332/
https://www.ncbi.nlm.nih.gov/pubmed/37880182
http://dx.doi.org/10.1136/jitc-2023-007010

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