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Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) is a key intracellular enzyme that participates in nicotinamide adenine dinucleotide (NAD) homeostasis as well as a released cytokine (eNAMPT) that is elevated in inflammatory conditions and in cancer. In patients with breast cancer, circula...

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Detalles Bibliográficos
Autores principales:	Travelli, Cristina, Colombo, Giorgia, Aliotta, Martina, Fagiani, Francesca, Fava, Natalia, De Sanctis, Rita, Grolla, Ambra A, Garcia, Joe G N, Clemente, Nausicaa, Portararo, Paola, Costanza, Massimo, Condorelli, Fabrizio, Colombo, Mario Paolo, Sangaletti, Sabina, Genazzani, Armando A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603332/ https://www.ncbi.nlm.nih.gov/pubmed/37880182 http://dx.doi.org/10.1136/jitc-2023-007010

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